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Biotech GmbH(\u745f\u53ef\u751f\u7269)\u7684\u63a8\u5e7f\u5728\u6b27\u6d32\u5f97\u5230\u5e7f\u6cdb\u5e94\u7528\uff0c\u5b83\u4e5f\u505a\u4e3a\u9996\u4e2a\u7ecf\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6\u8fdb\u53e3\u6ce8\u518c\u7684\u4e73\u817a\u764c\u5206\u5b50\u5206\u578b\u8bd5\u5242\u76d2\uff0c\u7531\u6570\u95ee\u751f\u7269\u5728\u4e2d\u56fd\u5f00\u59cb\u63a8\u5e7f\u3002\u95ee\u590d\u6790\u00ae\u662f\u6570\u95ee\u751f\u7269\u57fa\u4e8e\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\u72ec\u5bb6\u8f6c\u8ba9\u53d6\u5f97\u7684\u590d\u65e6\u5206\u578b\u4e13\u5229\u6280\u672f\u4e0e\u590d\u65e6\u80bf\u7624\u533b\u9662\u90b5\u5fd7\u654f\u6559\u6388\u56e2\u961f\u5408\u4f5c\u5f00\u53d1\u7684\u4e09\u9634\u6027\u4e73\u817a\u764c\u7cbe\u51c6\u5206\u578b\u4ea7\u54c1\u3002<\/p>\n\n\n\n<p>\u672c\u6b21\u53d1\u5e03\u7684\u516d\u9879\u7814\u7a76\u6210\u679c\u4e2d\uff0cAbstract#75\uff08#PB-075\uff09\u662f<strong>\u610f\u5927\u5229\u6bd4\u8428\u5927\u5b66Cristian Scatena\u6559\u6388<\/strong>\u7684\u7814\u7a76\uff0c\u5229\u7528\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u6784\u5efa\u4e86\u9884\u6d4bHER2\u9633\u6027\u4e73\u817a\u764c\u65b0\u8f85\u52a9\u5316\u7597\u80fd\u5426\u53d6\u5f97\u75c5\u7406\u5b8c\u5168\u7f13\u89e3\uff08pCR\uff09\u7684\u51b3\u7b56\u6811\u6a21\u578b\uff0c\u53d1\u73b0\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u53ef\u4ee5\u51c6\u786e\u533a\u5206\u65b0\u8f85\u52a9\u5316\u7597\u540e\u8fbe\u5230pCR\u548c\u672a\u8fbepCR\u7684HER2\u9633\u6027\u4e73\u817a\u764c\u60a3\u8005\uff0c\u662f\u5347\u9636\/\u964d\u9636\u6cbb\u7597\u7684\u6709\u529b\u51b3\u7b56\u5de5\u5177\u3002<\/p>\n\n\n\n<p>Abstract#274\uff08#PB-090\uff09\u662f\u7531<strong>\u610f\u5927\u5229Veneto\u80bf\u7624\u7814\u7a76\u6240\u80bf\u7624\u5185\u79d1Simona Frezzini\u6559\u6388<\/strong>\u5b8c\u6210\u7684\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u7814\u7a76\uff0c\u53d1\u73b0\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u68c0\u6d4b\u53ef\u7528\u4e8eIHC\/ISH\u4e0d\u6613\u786e\u5b9a\u7684\u75c5\u4f8b\uff0c\u5305\u62ec\u533a\u5206HER2\u4f4e\u8868\u8fbe\u6837\u672c\uff0c\u4ece\u800c\u66f4\u597d\u5730\u6307\u5bfc\u6cbb\u7597\u3002\u4e0e IHC \u76f8\u6bd4\uff0c\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u68c0\u6d4b\u4f4e\u8868\u8fbe\u7684<em>PGR<\/em>\u548c\u9ad8\u8868\u8fbe\u7684<em>MKI67<\/em>\u53ef\u80fd\u4e0eOncoType Dx\u9ad8\u98ce\u9669RS\u8bc4\u5206\u6709\u66f4\u597d\u7684\u76f8\u5173\u6027\uff0c\u66f4\u503e\u5411\u4e8e\u5316\u7597\u83b7\u76ca\u3002<\/p>\n\n\n\n<p>Abstract#278\uff08#PB-094\uff09\u662f<strong>\u8377\u5170\u4f0a\u62c9\u65af\u59c6\u65af\u5927\u5b66\u533b\u5b66\u4e2d\u5fc3\u75c5\u7406\u79d1Ximena Navarro\u6559\u6388<\/strong>\u5b8c\u6210\u7684\u6709\u5173HER2\u4f4e\u8868\u8fbe\u7814\u7a76\uff0c\u5728\u7ecf16\u4f4d\u75c5\u7406\u533b\u751f\u514d\u75ab\u7ec4\u5316\u5206\u522b\u9605\u7247\u786e\u5b9a\u7684\u6807\u51c6HER2\u975e\u9ad8\u8868\u8fbe\uff08\u5305\u62ecHER2-0\u53caHER2-low\uff09\u6837\u672c\u4e2d\uff0c\u7528\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u68c0\u6d4bHER2 mRNA\u8868\u8fbe\uff0c\u53d1\u73b0\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u4e0e\u6240\u8ff0\u6807\u51c6IHC\u6709\u826f\u597d\u7684\u4e00\u81f4\u6027\u3002<\/p>\n\n\n\n<p>Abstract#305\uff08#PB-121\uff09\u662f<strong>\u8bfa\u4e01\u6c49\u5927\u5b66\u533b\u9662\u75c5\u7406\u79d1Emad Rakha\u6559\u6388<\/strong>\u9886\u5bfc\u7684\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u7528\u4e8eHER2\u9633\u6027\u4e73\u817a\u764c\u6837\u672c\u7684\u7814\u7a76\uff0c\u6839\u636e\u4e34\u5e8a\u6cbb\u7597\u7ed3\u5c40\u7684\u5206\u6790\uff0c\u53d1\u73b0\u4e0e\u514d\u75ab\u7ec4\u5316\u65b9\u6cd5\u76f8\u6bd4\uff0c\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u68c0\u6d4b\u5728\u5b9a\u4e49\u548c\u8bc6\u522bHER2\u9633\u6027\u4e73\u817a\u764c\u60a3\u8005\u65b9\u9762\u66f4\u51c6\u786e\uff0c\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u68c0\u6d4bHER2\u9633\u6027\u60a3\u8005\u53ef\u663e\u8457\u83b7\u76ca\u4e8e\u6297HER2\u8f85\u52a9\u6cbb\u7597\uff0c\u800c\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u68c0\u6d4bHER2\u9634\u6027\u800cIHC\u68c0\u6d4bHER2\u9633\u6027\u7684\u60a3\u8005\u4e2d\u6297HER2\u8f85\u52a9\u6cbb\u7597\u672a\u53d6\u5f97\u663e\u8457\u6548\u679c\u3002<\/p>\n\n\n\n<p>Abstract#279\uff08#PB-095\uff09\u662f<strong>\u6cb3\u5317\u7701\u80bf\u7624\u533b\u9662\u75c5\u7406\u79d1\u5218\u6708\u5e73\u6559\u6388<\/strong>\u9886\u5bfc\u7684\u5c06\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u548cIHC\/FISH\u7528\u4e8e\u4e73\u817a\u6d78\u6da6\u6027\u5fae\u4e73\u5934\u72b6\u764cHER2\u72b6\u6001\u8bc4\u4f30\u7684\u7814\u7a76\uff0c\u63d0\u51fa\u5bf92023\u7248ASCO\/CAP HER2\u68c0\u6d4b\u6307\u5357\u7684\u6539\u8fdb\u5efa\u8bae\uff0c\u8ba4\u4e3a\u5bf9\u4e8e\u4e73\u817a\u6d78\u6da6\u6027\u5fae\u4e73\u5934\u72b6\u764c\u60a3\u8005\uff0c\u226510%\u7684\u6d78\u6da6\u6027\u80bf\u7624\u7ec6\u80de\u4e2d\u5f3a\u70c8\u7684\u57fa\u5e95\u5916\u4fa7\u819c\u67d3\u8272\u8868\u660eHER2\u9633\u6027\uff0c\u53ef\u76f4\u63a5\u5224\u8bfb\u4e3a3+\uff1b\u226510%\u7684\u6d78\u6da6\u6027\u80bf\u7624\u7ec6\u80de\u4e2d\u57fa\u5e95\u5916\u4fa7\u819c\u4e2d\u7b49-\u5f31\u67d3\u8272\u5e94\u5f52\u7c7b\u4e3a2+\uff0c\u5e76\u53ef\u91c7\u7528\u5988\u5988\u6cf0\u8c31<sup>\u00ae<\/sup>\u68c0\u6d4b\u786e\u5b9aHER2\u72b6\u6001\u3002<\/p>\n\n\n\n<p>Abstract#284\uff08#PB-100\uff09\u662f<strong>\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\u90b5\u5fd7\u654f\u6559\u6388\u3001\u6768\u6587\u6d9b\u6559\u6388<\/strong>\u548c\u6570\u95ee\u751f\u7269\u7684\u5408\u4f5c\u7814\u7a76\uff0c\u9a8c\u8bc1\u4e86\u6570\u95ee\u751f\u7269\u7684\u95ee\u590d\u6790\u00ae\u4ea7\u54c1\uff0c\u663e\u793a\u95ee\u590d\u6790\u00ae\u662f\u4e00\u79cd\u65b0\u578b\u53ef\u9760\u7684\u4e09\u9634\u6027\u4e73\u817a\u764c\u5206\u5b50\u5206\u578b\u4ea7\u54c1\uff0c\u5e76\u63d0\u793a\u5e94\u8fdb\u4e00\u6b65\u8bc4\u4f30HER2\u4f4e\u8868\u8fbe\u7684\u4e09\u9634\u6027\u4e73\u817a\u764c\u5728LAR\u4e9a\u578b\u4e2d\u7684\u5bcc\u96c6\u60c5\u51b5\u3002<\/p>\n\n\n\n<p>\u6570\u95ee\u751f\u7269\u8463\u4e8b\u957f\u517c\u5fb7\u56fd\u745f\u53ef\u751f\u7269CEO\u5f20\u4ee5\u54f2\u535a\u58eb\u8868\u793a\uff0c\u201c\u5988\u5988\u6cf0\u8c31\u00ae\u4f5c\u4e3a\u4e00\u4e2a\u521b\u65b0\u8bca\u65ad\u4ea7\u54c1\uff0c\u5df2\u7ecf\u670930\u591a\u7bc7\u56fd\u9645\u8bba\u6587\u548c\u4f1a\u8bae\u6458\u8981\u652f\u6301\u5176\u4f18\u5f02\u7684\u6027\u80fd\uff0c\u672c\u5c4aEBCC\u4e0a\u53d1\u5e03\u7684\u6765\u81ea\u6b27\u6d32\u548c\u4e2d\u56fd\u7684\u7814\u7a76\u6210\u679c\uff0c\u4e3a\u5988\u5988\u6cf0\u8c31\u00ae\u589e\u6dfb\u4e86\u66f4\u591a\u7684\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff0c\u5c24\u5176\u4f53\u73b0\u4e86\u5176\u5728HER2\u68c0\u6d4b\u7684\u4f18\u52bf\u3002\u4e09\u9634\u6027\u4e73\u817a\u764c\u590d\u65e6\u5206\u578b\u662f\u90b5\u6559\u6388\u56e2\u961f\u7684\u4e00\u9879\u91cc\u7a0b\u7891\u5f0f\u7684\u91cd\u5927\u7a81\u7834\uff0c\u57fa\u4e8e\u8fd9\u4e00\u7814\u7a76\u6210\u679c\u7684\u95ee\u590d\u6790\u00ae\u4ea7\u54c1\u5df2\u7ecf\u4e0a\u5e02\u3002\u6570\u95ee\u751f\u7269\u7684\u6301\u7eed\u521b\u65b0\u80fd\u529b\u662f\u8fbe\u6210\u56fd\u5185\u53ca\u56fd\u9645\u5e02\u573a\u53cc\u5411\u4e92\u52a8\u7684\u5f3a\u5927\u57fa\u7840\uff0c\u6211\u4eec\u671f\u5f85\u95ee\u590d\u6790\u00ae\u548c\u5988\u5988\u6cf0\u8c31\u00ae\u60e0\u53ca\u66f4\u591a\u4e73\u817a\u764c\u60a3\u8005\u3002\u201d<\/p>\n\n\n\n<p><strong>\u5173\u4e8e<\/strong><strong>\u5988\u5988\u6cf0\u8c31\u00ae<\/strong><strong><\/strong><\/p>\n\n\n\n<p>\u5988\u5988\u6cf0\u8c31\u00ae\uff08MammaTyper\u00ae\uff09\uff08\u901a\u7528\u540d\uff1a\u4eba\u4e73\u817a\u764c\u5206\u5b50\u5206\u578b\u68c0\u6d4b\u8bd5\u5242\u76d2\uff1bNMPA\u6ce8\u518c\u8bc1\u53f7\uff1a\u56fd\u68b0\u6ce8\u8fdb20233400600\uff09\u662f\u4e00\u6b3e\u57fa\u4e8e\u8367\u5149\u5b9a\u91cf\u57fa\u56e0\u6269\u589e\u6280\u672f\u68c0\u6d4b\u591a\u57fa\u56e0\u8868\u8fbe\u7528\u4e8e\u4e73\u817a\u764c\u5206\u5b50\u5206\u578b\u7684\u8bd5\u5242\u76d2\uff0c\u88ab\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6\u9002\u7528\u4e8e\u514d\u75ab\u7ec4\u5316\uff08IHC\uff09\u4e0d\u6613\u5224\u5b9a\u6216\u7ed3\u679c\u4e0d\u6ee1\u610f\u3001\u4ee5\u53caIHC\u7ed3\u679c\u4e0e\u6cbb\u7597\u9884\u671f\u6709\u8f83\u5927\u5dee\u522b\u7684\u75c5\u4f8b\uff0c\u4ee5\u8fdb\u4e00\u6b65\u8f85\u52a9\u5224\u65ad\u4e73\u817a\u764c\u5206\u5b50\u5206\u578b\u3002\u5988\u5988\u6cf0\u8c31\u00ae\uff08MammaTyper\u00ae\uff09\u65e0\u9700\u75c5\u7406\u4eba\u5de5\u9605\u7247\uff0c\u800c\u662f\u5bf9\u591a\u57fa\u56e0\u8868\u8fbe\u7cbe\u51c6\u5b9a\u91cf\uff0c\u5177\u6709\u9ad8\u5ea6\u7684\u53ef\u91cd\u590d\u6027\uff0c\u4fdd\u8bc1\u68c0\u6d4b\u7ed3\u679c\u7684\u5ba2\u89c2\u6027\u548c\u53ef\u9760\u6027\uff0c\u907f\u514d\u4e86\u4f20\u7edf\u4eba\u5de5\u75c5\u7406\u9605\u7247\u4e2d\u7684\u7ecf\u9a8c\u3001\u4e60\u60ef\u3001\u4e13\u4e1a\u5ea6\u548c\u5173\u6ce8\u5ea6\u7b49\u4eba\u4e3a\u4e3b\u89c2\u56e0\u7d20\uff0c\u4ece\u800c\u4f7f\u4e73\u817a\u764c\u5206\u578b\u66f4\u7cbe\u51c6\uff0c\u6307\u5bfc\u6cbb\u7597\u8fbe\u5230\u66f4\u597d\u7684\u6548\u679c\u3002\u9664\u4e86\u7cbe\u51c6\u5206\u578b\u4e4b\u5916\uff0c\u5728\u56fd\u5185\u5916\u7684\u4e09\u5341\u591a\u9879\u4e34\u5e8a\u7814\u7a76\u548c\u53d1\u8868\u8bba\u6587\u4e2d\uff0c\u5988\u5988\u6cf0\u8c31\u00ae\uff08MammaTyper\u00ae\uff09\u4e5f\u5728\u8154\u9762\u4e9a\u578b\u9884\u540e\u6307\u5bfc\u5316\u7597\u3001\u9884\u6d4b\u539f\u7814Oncotype Dx 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